Once inside human cells, HIV integrates the viral genome ... a potential explanation for the evolution of the unique HIV capsid structure: its conical shape might be necessary to break the nuclear ...

Supercomputer simulations have revealed how changes in the shape of the HIV-1 capsid protein may help the virus squeeze its ...

Another important discovery was an intricate RNA structure near the critical ... detailed map of the translational landscape of HIV-1 infected cells but also a wealth of potential targets for ...

Two research teams led by Warner Greene at the Gladstone Institutes in San Francisco have demonstrated that the vast majority of CD4 T cells in lymphoid tissues, despite their ability to resist full ...

In contrast, lentiviruses such as human immunodeficiency virus (HIV) do not depend on host cell mitosis to access the nucleus. As a consequence, lentviruses are able to replicate within non ...

When we know the structure of a protein, we can attempt to design small drug molecules to bind to it and block its function. The power of this approach has been shown in the battle against HIV and ...

This molecule, known as EBC-46, works by temporarily activating the HIV virus in the affected cells as they hide so that the body’s immune system can remove the virus, according to a study published ...

Researchers at The Wistar Institute’s HIV Cure and Viral Diseases Center have successfully identified a new approach using natural killer (NK) cells to target and kill the HIV-positive cells that ...